ELITE DIGEST-HELP

Biocell Medic proudly presents Elite Digest-Help, an innovative nutraceutical formula for a healthy digestive system. This fermented powder contains 37 organic fruits, berries, and vegetables, along with powerful active ingredients. Elite Digest-Help offers a wide range of benefits, including improved digestion, balanced gut flora, reduced inflammation, and strengthened immunity. It also supports cardiovascular health, metabolism, and the recovery of intestinal tissues. The formula’s advanced fermentation processes enhance nutrient absorption and provide high levels of microfibers. Elite Digest-Help is easy to take and promotes overall well-being.

Biocell Medic is very proud to present one of the world most sophisticated innovative epic nutraceutical formula for a vital healthy digestive system named Elite Digest-Help. Biocell Medic is positive that this nutraceutical supplement is beyond all your expectations.

We have spent over 11 years to create a phenomenal broad spectrum outstanding scientific based nutraceutical formula to ensure an optimal healthy digestive system beyond all imagination to provide exceptional synergetic holistic vitality wellness to your digestive system and much more beyond.

Elite Digest-Help contributes to the recovery of the intestinal wall and the creation of a balanced gut flora, promotes metabolism and inhibits chronic inflammation and anti-swelling, protects against oxidative damage, reinforces and balances the immune system, recovers the intestinal villi to name a few of the beneficial effects of our unique formula. Please read on to learn of a multitude of healthy effects.

Elite Digest-help is a fermented powder of 37 kinds of organic fruits, berries and vegetables namely: partially hydrolysed guar gum, apple, carrot, mulberry, radish, pineapple, orange, lemon, beetroot, prune, plum, passionfruit, watermelon, wolfberry, grapefruit, grape, peach, acerola, cranberry, strawberry, raspberry, cherry, chokeberry, blackcurrant, gooseberry, bilberry, pear, pomegranate, banana, papaya, lychee, melon, tomato, asparagus, jujube, hawthorn and broccoli sprout. We have also added SAC, S-allyl cysteine, and SMAC, S-allyl mercaptocysteine. These are super pure active substances from fermented aged black garlic and bioactive compounds 6-gingerol, 6-shogaol, and 6-paradol from fermented ginger, and also super pure combination of ultra-vegan fermented N-acetyl l- glutamine & L-Glutamine, and 3 greatest adaptogens such as fermented Ashwaganda, Jiaogulan and Curcumin. Additionally, we have added fermented natural matrix GABA and fermented L-Theanine, plus natural exotic fruits flavours and pure Stevia leaf extract. 

Our unique fermented Elite Digest-Help formula provides significantly more microfiber per serving than other greens and fruits, berries powder supplements on the global markets. We have developed an amazing advanced innovative and bioactive compound with our unique supercharging quantum physics biofield and bio magnetics frequencies energy, and our high-tech processing systems, to create vibrational substances which is important for digestive and cardiovascular health and very much more. It contains more than 85% microfibres and is a promising nutrient-rich prebiotic which creates great balance in the microbiome. 

Our unique advanced fermentation processes increase not only the bioavailability of nutrients, but also that of the secondary metabolites and active compounds from fruits, berries and vegetables. Our epic fermentation processes mimic the intestinal flora-mediated transformation of fruits, berries and vegetables compounds into their bioactive form. Certain fruits, berries and vegetables contain loads of natural chemical compounds, such as saponin glycosides, which are produced in a wide variety of species. These naturally occurring glycosides are converted into their more active form by lactic acid fermentation advanced processes and with our super high-tech innovative supercharging conversion processes, also known as deglycosylation. It reduces the molecular size of the saponins and with supercharging makes them very much easier to absorb and to pass through cell membranes very much more easily. 

Elite Digest-Help assists the body substantially to pre-digest the fruits, berries and vegetables. This results in a strong improved absorption of nutrients, flavonoids and microfibres, polyphenols from fruits-berries and vegetables. Due to the unique 5-stage fermentation processes these substances are split into more accessible super micro pieces. The polyphenols and flavonoids are important antioxidants that are directly effective in the intestine and to prevent inflammation. 

Elite Digest-Help contains water-soluble nutrients and a mixture of different types of microfibres that are more easily digested by the different strains of trillions of the good bacteria of our microbiome. The wide variety of microfibres provides an effective menu for most of the microbiome. It stimulates the growth of native probiotics, thus contributing to a balanced microbiome eco-system. Other prebiotics on the global market can cause symptoms such as bloating and flatulence etc as they do not contain microfibers.

These smaller micro flavonoid polyphenols are very much better absorbed by the body and have a complementary effect on prebiotics in their aglycone form, have anti-inflammatory and anti-swelling properties, help to calm down and balance the immune system. It also contains SOD-like 

substances, these are small and very active plant molecules with a similar SOD-activity, such as hesperitin (aglycon form of hesperidin) and other transformed flavonoids. These SOD-like substances are very well structured and that makes them very much easily absorbed by the body, stable and resistance against gastric acid, bile salts and many different enzymes, responsible for the elimination of O2.- or superoxide anion. The microfibres in our Elite Digest-help are enzymatically converted into short-chain fatty acids (SCFAs). These provide an important source of energy for the colonocytes which are renewed constantly. The enzymes stimulate the transcription of enzyme-producing genes, increasing the number of enzymes and thus stimulating the further digestion of fibres in foods. 

Advantages of Elite Digest-Help;

  • significantly improves and supports a healthy digestion, 
  • prevents your body against chronic inflammation diseases especially in the gut, 
  • prevents gastrointestinal complaints, 
  • supports a neuroprotective effect, 
  • balances and contributes to a healthy beneficial effect on the microbiome, 
  • contributes to the recovery of the intestinal wall 
  • creates a balanced gut flora, 
  • beneficial effect on cardiovascular diseases
  • promotes metabolism 
  • inhibits chronic inflammation 
  • reduces significantly both IBD and IBS symptoms  
  • activates healing intestinal tissues processes 
  • anti-swelling effect
  • protects against oxidative damage, 
  • reinforces and balances the immune system, 
  • recovers the intestinal villi.
  • beneficial effect on cardiovascular diseases
  • increases the effect powerful antioxidant, 
  • may slow cognitive decline, 
  • beneficial effect on myopia, 
  • slows down the process for skin aging, 
  • increases energy levels  
  • supports the function of the liver,
  • detoxifies your body, 
  • reduces age-related macular degeneration, 
  • increases levels of vitamins, minerals and amino acids in the blood as well as certain special powerful antioxidants, 
  • may reduce appetite, 
  • promotes satiety,  
  • decreases the absorption of sugar and bad cholesterol in the stomach, leading to blood sugar control  
  • contributes to decreased bad cholesterol and triglyceride levels 
  • relieves morning sickness and menstrual symptoms (PMS), 
  • relieves migraine, 
  • anti-hyperglycaemic properties, 
  • anti-platelet aggregation effects, 
  • decreases the blood pressure, 
  • reduces the risk of diabetes, 
  • improves the memory, 
  • increases learning capabilities, 
  • promotes mental clarity and focus, 
  • combats anxiety, 
  • reduces pain, 
  • lowers the risk of obesity, 
  • stress relief effect,  
  • helps to support relaxation without drowsiness,  
  • prevents insomnia. 

Elite Digest-help IMPROVE DIGESTION & NUTRIENT CONTENT

Our State-of-the-art fermentation processes break down nutrients into more easily digestible forms. 

Elite Digest-Help with supercharged ingredients effectively pre-digests the vegetables, fruit and berries and they in turn become more bioavailable and easier for you to absorb. This results in higher nutrient content – vitamin and mineral and amino acids levels are enhanced during the fermentation processes and all matrix of the nutrients and polyphenols are preserved. Elite Digest-help is packed with phytonutrients to help promote healthy energy levels without the crash you get from caffeine, sugar or energy drinks. The vitamins, minerals and microfibres will refuel your brain to help support focus and clearer thinking. 

So, whether you’re 22 or 100 years old, Elite Digest-Help fermented fruit, berries and vegetables epic formula has exceptional health benefits to offer you: improved nutrition, energy, digestion, immunity, and mental and physical wellbeing. This fermented formula with supercharged ingredients is absolutely one of the most effective purest and potent formula for the digestive and intestinal health ever created!

Dosage

Elite Digest-Help is easy to take. Just put your daily dose of powder, 15 gr, in 300 ml liquid such as water, juice, etc. Drink at least one full glass of water directly afterwards. 

For maximum effect, take Elite Digest-Help between breakfast and lunch, or between lunch and dinner.

Please note that Elite Digest-Help may not be put in smoothies/electric machines/mixers. 

However, you may add Elite Digest-Health to a prepared smoothie and mix the product manually from your shaker into the smoothie.

References

  • Belwal T, Nabavi SF, Nabavi SM, Habtemariam S. Dietary anthocyanins and insulin resistance: when food becomes a medicine. Nutrients 2017; 9: 1111 doi:10.3390/nu9101111.
  • Bendokas V Skemiene K, Trumbeckaite S, Stanys V, Passamonti S, Borutaite V, Liobikas J. Anthocyanins: From plant pigments to health benefits at mitochondrial level. Crit Rev Food Sci Nutr 2019; DOI: 10.1080/10408398.2019.1687421.
  • Cassidy A. Berry anthocyanin intake and cardiovascular health. Mol Aspects Med 2018; 61:76-82.
  • Chambers ES, Preston T, Frost G, Morrison DJ. Role of gut microbiota-generated short chain fatty acids in metabolic and cardiovascular health. Curr Nutr Rep 2018; 7:198-206
  • Dabeek WM, Marra MV. Dietary quercetin and kaempferol: bioavailability and potential cardiovascular-related bioactivity in humans. Nutrients 2019; 11:2288, doi:10.3390/nu11102288
  • Fechner A, Kiehntopf M, Jahreis G. The Formation of short-chain fatty acids is positively associated with the blood lipid–lowering effect of lupin kernel fiber in moderately hypercholesterolemic adults. J Nutr 2014; 144:599-607.
  • Hwang JY, Shieh DE, Shyu YS, Hsu CK, Lin CW. Antidiabetic, antihyperlipidemic, and antioxidant activities of mulberry lees fermented products in diabetic mice. J Food Sci 2018; 83(11):2866-72.
  • Istas G Feliciano RP, Weber T, Garcia-Villalba R, Tomas-Barberan F, Heiss C, Rodriguez-Mateos A. Plasma urolithin metabolites correlate with improvements in endothelial function after red raspberry consumption: A double-blind randomized controlled trial. Arch Biochem Biophys 2018; 651:43-51.
  • Ivey KL Chan AT, Izard J, Cassidy A, Rogers GB, Rimm EB. Role of dietary flavonoid compounds in driving patterns of microbial community assembly. mBio 2019; 10:e01205-19. Hernandez MAG et al. Nutrients 2019; 11:1943 doi:10.3390/nu11081943.
  • Kamiya K, Kobashi H, Fujiwara K, Ando W, Shimizu K. Effect of fermented bilberry extracts on visual outcomes in eues w ith myopia. A prospective, randomized placebo-controlled study. J Ocul Pharmacol Ther 2013; 29(3):356-9.
  • Lavefve L, Howard LR, Carbonero F. Berry polyphenols metabolism and impact on human gut microbiota and health. Food Functi 2020; 11:45-6
  • Perez-Vizcaino F, Duarte. Flavonols and cardiovascular disease. J Mol Aspects Med 2010; 31:478-94.
  • Wang D Wei X, Yan X, Jin T, Ling W. Protocatechuic Acid, a metabolite of anthocyanins, inhibits monocyte adhesion and reduces atherosclerosis in apolipoprotein E-deficient mice. J Agric Food Chem 2010; 58:12722-8.
  • Martens EC, Lowe EC, Chiang H, Pudlo N, Wu M, McNulty NP, Abbott DW, Henrissat B, Gilbert H, Bolam DN, Gordon JI, Recognition and degradation of plant cell wall polysaccarides by two Human Gut symbionts Plos Biol 9(12): e1001221. doi:10.1371/journal.pbio.1001221
  • P Talamond , M Noirot, A de Kochko; The mechanism of action of alfa amylase from Lactobacillus fermentum on maltooligosaccharides Journal of Chromatography B, 834 (2006) 42–47
  • Perez-Vizcaino F, Duarte. Flavonols and cardiovascular disease. J Mol Aspects Med 2010; 31:478-94.
  • SA Poeker , A Geirnaert , L Berchtold , A Greppi , L  Krych  R E Steinert, T de Wouters, C Lacroix : Understanding the prebiotic potential of different dietary fibers using an in vitro continuous adult fermentation model (PolyFermS) ; 2018 Mar 12;8(1):4318. doi: 10.1038/s41598-018-22438-y
  • Wang D Wei X, Yan X, Jin T, Ling W. Protocatechuic Acid, a metabolite of anthocyanins, inhibits monocyte adhesion and reduces atherosclerosis in apolipoprotein E-deficient mice. J Agric Food Chem 2010; 58:12722-8.
  • Yukina Kawabata, Misato Kanaoka, Chika Bogaki, Kyoko Suzuki, Takafumi Iguchi, Motoko Takaoka and Toshiro Watanabe. Effects of ginger koji intake on skin surface temperature for young women sensitive to cold temperatures. Brew. Soc. Japan Vol.108, No.10, pg. 778-786 (2013)
  • Han-Chung Lien, Wei Ming Sun, Yen-Hsueh Chen, Hyerang Kim, William Hasler, Chung Owyang. Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection. Am J Physiol Gastrointest Liver Physiol . 2003 Mar;284(3):G481-9.
  • T Vutyavanich 1, T Kraisarin, R Ruangsri. Ginger for nausea and vomiting in pregnancy: randomized, double-masked, placebo-controlled trial. Obstet Gynecol. 2001 Apr;97(4):577-82
  • Julie L Ryan , Charles E Heckler, Joseph A Roscoe, Shaker R Dakhil, Jeffrey Kirshner, Patrick J Flynn, Jane T Hickok, Gary R Morrow. Ginger (Zingiber officinale) reduces acute chemotherapy-induced nausea: a URCC CCOP study of 576 patients. Support Care Cancer . 2012 Jul;20(7):1479-89.
  • Mehrnaz Nikkhah Bodagh, Iradj Maleki, and Azita Hekmatdoost. Ginger in gastrointestinal disorders: A systematic review of clinical trials. Food Sci Nutr. 2019 Jan; 7(1): 96–108.
  • Keng-Liang Wu 1, Christopher K Rayner, Seng-Kee Chuah, Chi-Sin Changchien, Sheng-Nan Lu, Yi-Chun Chiu, King-Wah Chiu, Chuan-Mo Lee. Effects of ginger on gastric emptying and motility in healthy humans. Eur J Gastroenterol Hepatol. 2008 May;20(5):436-40.
  • Attilio Giacosa, Davide Guido, Mario Grassi, Antonella Riva, Paolo Morazzoni, Ezio Bombardelli, Simone Perna, Milena A. Faliva, and Mariangela Rondanelli. The Effect of Ginger (Zingiber officinalis) and Artichoke (Cynara cardunculus) Extract Supplementation on Functional Dyspepsia: A Randomised, Double-Blind, and Placebo-Controlled Clinical Trial. Evid Based Complement Alternat Med. 2015; 2015: 915087.
  • Asad Mahmood Khan, Muhammad Shahzad, M B Raza Asim, Muhammad Imran, Arham Shabbir. Zingiber officinale ameliorates allergic asthma via suppression of Th2-mediated immune response. Pharm Biol. 2015 Mar;53(3):359-67.
  • Elizabeth A. Townsend, Matthew E. Siviski, Yi Zhang. Effects of Ginger and Its Constituents on Airway Smooth Muscle Relaxation and Calcium Regulation. Am J Respir Cell Mol Biol. 2013 Feb;48(2):157-63.
  • Kardan M, Rafiei A, Ghaffari J, Valadan R, Morsaljahan Z, Haj-ghorbani ST. Effect of ginger extract on expression of GATA3, T-bet and ROR-γt in peripheral blood mononuclear cells of patients with allergic asthma. Allergol Immunopathol (Madr). 2019;47(4):378-385.
  • Rodsarin Yamprasert, Waipoj Chanvimalueng, Nichamon Mukkasombut, and Arunporn Itharat. Ginger extract versus Loratadine in the treatment of allergic rhinitis: a randomized controlled trial. BMC Complement Med Ther. 2020; 20: 119
  • Janet L. Funk, Jennifer B. Frye, Janice N. Oyarzo, Jianling Chen, Huaping Zhang, and Barbara N. Timmermann. Anti-Inflammatory Effects of the Essential Oils of Ginger (Zingiber officinale Roscoe) in Experimental Rheumatoid Arthritis. Pharma Nutrition. 2016 Jul; 4(3): 123–131.
  • Chien-Kei Wei, Yi-Hong Tsai, Michal Korinek, Pei-Hsuan Hung, Mohamed El-Shazly, Yuan-Bin Cheng, Yang-Chang Wu, Tusty-Jiuan Hsieh, and Fang-Rong Chang. 6-Paradol and 6-Shogaol, the Pungent Compounds of Ginger, Promote Glucose Utilization in Adipocytes and Myotubes, and 6-Paradol Reduces Blood Glucose in High-Fat Diet-Fed Mice. Int J Mol Sci. 2017 Jan; 18(1): 168.
  • Hung-Cheng Shih, Ching-Yuh Chern, Ping-Chung Kuo, You-Cheng Wu, Yu-Yi Chan, Yu-Ren Liao, Che-Ming Teng, and Tian-Shung Wu. Synthesis of Analogues of Gingerol and Shogaol, the Active Pungent Principles from the Rhizomes of Zingiber officinale and Evaluation of Their Anti-Platelet Aggregation Effects. Int J Mol Sci. 2014 Mar; 15(3): 3926–3951.
  • Yu-Ren Liao, Yann-Lii Leu, Yu-Yi Chan, Ping-Chung Kuo, and Tian-Shung Wu. Anti-Platelet Aggregation and Vasorelaxing Effects of the Constituents of the Rhizomes of Zingiber officinale. Molecules. 2012 Aug; 17(8): 8928–8937.
  • Faizul Azam, Abdualrahman M Amer, Abdullah R Abulifa, and Mustafa M Elzwawi. Ginger components as new leads for the design and development of novel multi-targeted anti-Alzheimer’s drugs: a computational investigation. Drug Des Devel Ther. 2014; 8: 2045–2059.
  • Naritsara Saenghong, Jintanaporn Wattanathorn, Supaporn Muchimapura,  Terdthai Tongun,  Nawanant Piyavhatkul,  Chuleratana Banchonglikitkul,  and Tanwarat Kajsongkram . Zingiber officinale Improves Cognitive Function of the Middle-Aged Healthy Women. Evid Based Complement Alternat Med. 2012; 2012: 383062.
  • Gao-Feng Zeng, Zhi-Yong Zhang, Li Lu, De-Qiang Xiao, Shao-Hui Zong, Jian-Ming He. Protective effects of ginger root extract on Alzheimer disease-induced behavioral dysfunction in rats. Rejuvenation Res . 2013 Apr;16(2):124-33. doi: 10.1089/rej.2012.1389.
  • Ana L. Col´ın-Gonz´alez, Ricardo A. Santana, Carlos A. Silva-Islas, Maria E. Ch´anez-C´ardenas, Abel Santamarıa, and Perla D.Maldonado. The Antioxidant Mechanisms Underlying the Aged Garlic Extract- and S-Allylcysteine-Induced Protection. Oxidative Medicine and Cellular Longevity Volume 2012, Article ID 907162, 16 pages, doi:10.1155/2012/907162
  • Ae Wha Ha and Woo Kyoung Kim. Antioxidant mechanism of black garlic extract involving nuclear factor erythroid 2-like factor 2 pathway. Nutrition Research and Practice 2017;11(3):206-213
  • Ae Wha Ha, Tian Ying and Woo Kyoung Kim. The effects of black garlic (Allium satvium) extracts on lipid metabolism in rats fed a high fat diet. Nutrition Research and Practice 2015;9(1):30-36
  • -Shunsuke Kimura, Yen-Chen Tung, Min-Hsiung Pan, Nan-Wei Su, Ying-Jang Lai, Kuan-Chen Cheng. Review Article Black garlic: A critical review of its production, bioactivity, and application. Journal of food and drug analysis 25 (2017) 62-70
  • Jeong YY, Ryu JH, Shin JH, Kang MJ, Kang JR, Han J, Kang D. Comparison of anti-oxidant and anti-inflammatory effects between fresh and aged black garlic extracts. Molecules 2016; 21:430.
  • Ha AW, Ying T, Kim WK. The effects of black garlic (Allium sativum) extracts on lipid metabolism in rats fed a high fat diet. Nutr Res Pract 2015; 9:30e6.
  • Kim MJ, Yoo YC, Kim HJ, Shin SK, Sohn EJ, Min AY, Sung NY, Kim MR. Aged black garlic exerts anti-inflammatory effects by decreasing no and proinflammatory cytokine production with less cytotoxicity in LPS-stimulated RAW 264.7 macrophages and LPS-induced septicemia mice. J Med Food 2014; 17:1057e63
  • K Ried, OR Frank and NP Stocks. Aged garlic extract reduces blood pressure in hypertensives: a dose–response trial. European Journal of Clinical Nutrition (2013) 67, 64–70
  • Karin Ried, Nikolaj Travica, Avni Sali. The effect of aged garlic extract on blood pressure and other cardiovascular risk factors in uncontrolled hypertensives: the AGE at Heart trial. Integrated Blood Pressure Control, 27 January 2016.
  • Nutchareeporn Nillert, Wanassanun Pannangrong, Jariya Umka Welbat3, Wunnee Chaijaroonkhanarak, Kittisak Sripanidkulchai and Bungorn Sripanidkulchai. Neuroprotective Effects of Aged Garlic Extract on Cognitive Dysfunction and Neuroinflammation Induced by Amyloid in Rats. Nutrients: Published: 3 January 2017
  • Tan H.W.S., Sim A.Y.L., Long Y.C. Glutamine metabolism regulates autophagy-dependent mtorc1 reactivation during amino acid starvation. Nat. Commun. 2017;8:338. doi: 10.1038/s41467-017-00369-y. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
  • Souba W.W., Smith R.J., Wilmore D.W. Glutamine metabolism by the intestinal tract. J. Parenter. Enter. Nutr. 1985;9:608–617.doi: 10.1177/0148607185009005608. [PubMed] [CrossRef] [Google Scholar]
  • Kim M.H., Kim H. The roles of glutamine in the intestine and its implication in intestinal diseases. Int. J. Mol. Sci. 2017;18:1051. doi: 10.3390/ijms18051051. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
  • Cruzat V.F., Bittencourt A., Scomazzon S.P., Leite J.S., de Bittencourt P.I.H., Tirapegui J. Oral free and dipeptide forms of glutamine supplementation attenuate oxidative stress and inflammation induced by endotoxemia. Nutrition. 2014;30:602–611. doi: 10.1016 j.nut.2013.10.019. [PubMed] [CrossRef] [Google Scholar]
  • Li J., Ghazwani M., Liu K., Huang Y., Chang N., Fan J., He F., Li L., Bu S., Xie W., et al. Regulation of hepatic stellate cell proliferation and activation by glutamine metabolism. PLoS ONE. 2017;12:e0182679. doi: 10.1371/journal.pone.0182679. [PMC free article] [PubMed] [CrossRef] [Google Scholar]
  • Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation. Cruzat V, et al. Nutrients. 2018. PMID: 30360490 Free PMC article. Review.
  • Weitzel L.R., Wischmeyer P.E. Glutamine in critical illness: The time has come, the time is now. Crit. Care Clin. 2010;26:515–525. doi: 10.1016/j.ccc.2010.04.006. [PubMed] [CrossRef] [Google Scholar]
  • Watanabe M., Maernura K., Kanbara K., Tamayama T., Hayasaki H. GABA and GABA receptors in the central nervous system and other organs. Int. Rev. Cyrology. 2002;213:1–47. [PubMed] [Google Scholar]
  • -A.M. Abdou, S. Higashiguchi, K. Horie, M. Kim, H. Hatta, H. Yokogoshi
  • Relaxation and immunity enhancement effects of γ -Aminobutyric acid ( GABA ) administration in humansBiofactors, 26 (2006), pp. 201-208 View PDFCrossRefView Record in ScopusGoogle Scholar
  • P. Strandwitz, K.H. Kim, D. Terekhova, J.K. Liu, A. Sharma, J. Levering, D. McDonald, D. Dietrich, T.R. Ramadhar, A. Lekbua, N. Mroue, C. Liston, E.J. Stewart, M.J. Dubin, K. Zengler, R. Knight, J.A. Gilbert, J. Clardy, K. Lewis GABA-modulating bacteria of the human gut microbiota Nat. Microbiol. (2018)
  • Google Scholar
  • Shinsuke Hidese, et al. Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients. (2019)
  • Chanaka N Kahathuduwa, et al. l-Theanine and caffeine improve target-specific attention to visual stimuli by decreasing mind wandering: a human functional magnetic resonance imaging study. Nutr Res. (2018)
  • Shinsuke Hidese, et al. Effects of chronic l-theanine administration in patients with major depressive disorder: an open-label study. Acta Neuropsychiatr. (2017)
  • Javier Zaragoza, et al. Effects of acute caffeine, theanine and tyrosine supplementation on mental and physical performance in athletes. J Int Soc Sports Nutr. (2019)
  • David J White, et al. Anti-Stress, Behavioural and Magnetoencephalography Effects of an L-Theanine-Based Nutrient Drink: A Randomised, Double-Blind, Placebo-Controlled, Crossover Trial. Nutrients. (2016)
  • Chanaka N Kahathuduwa, et al. Acute effects of theanine, caffeine and theanine-caffeine combination on attention. Nutr Neurosci. (2017)
  • F L Dodd, et al. A double-blind, placebo-controlled study evaluating the effects of caffeine and L-theanine both alone and in combination on cerebral blood flow, cognition and mood. Psychopharmacology (Berl). (2015)
  • Park SK, et al. A combination of green tea extract and l-theanine improves memory and attention in subjects with mild cognitive impairment: a double-blind placebo-controlled study. J Med Food. (2011)
  • Nobre AC, Rao A, Owen GN. L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr. (2008)
  • Kimura K, et al. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. (2007)
  • Lu K, et al. The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans. Hum Psychopharmacol. (2004)
  • A Juszkiewicz, et al. The effect of L-theanine supplementation on the immune system of athletes exposed to strenuous physical exercise. J Int Soc Sports Nutr. (2019)
  • Hay E, Lucariello A, Contieri M, Esposito T, De Luca A, Guerra G, Perna A. Therapeutic effects of turmeric in several diseases: An overview. Chem Biol Interact 2019; 310:108729.
  • Soleimani V, Sahebkar A, Hosseinzadeh H. Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: Review. Phytother Res 2018; 32(6):985-995.
  • Stanić Z. Curcumin, a Compound from Natural Sources, a True Scientific Challenge – A Review. Plant Foods Hum Nutr 2017; 72(1):1-12.
  • Basnet P, Skalko-Basnet N. Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment. Molecules 2011; 16(6): 4567–4598.
  • Kunnumakkaraa AB, Harshaa C, Banika K, Vikkurthia R, Sailoa BL, Bordoloia D, Guptab SC, Aggarwalc BB. Is curcumin bioavailability a problem in humans: lessons from clinical trials? Expert Opin Drug Metab Toxicol 2019; 15(9):705-733.
  • Aggarwal B, Yuan W, Li S, Gupta SC. Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric. Mol Nutr Food Res 2013 Sep; 57(9):1529-42.
  • Ikpeama, Ahamefula, Onwuka GI, Nwankwo, Chibuzo. Nutritional Composition of Tumeric (Curcuma longa) and its Antimicrobial Properties. Int J Eng Res 2014; 5(10):1085-9.
  • Imoru A, Onibi GE, Osho IB. Nutritional and Biochemical Compositions of Turmeric (Curcuma longa Linn) Rhizome powder – A Promising Animal Feed Additive. Int J Eng Res 2018, 9(1):424-9.
  • Martini N. Turmeric. J Prim Health Care 2019; 11(2):187-188.
  • Lombardi N, Crescioli G, Maggini V, Ilaria Ippoliti I, Menniti-Ippolito F, Gallo E, Brilli V, Lanzi C, Mannaioni G, Firenzuoli F, Vannacci A. Acute liver injury following turmeric use in Tuscany: An analysis of the Italian Phytovigilance database and systematic review of case reports. Br J Clin Pharmacol 2020; 1–13.
  • Pianpumepong P, Anal AK, Doungchawee G, Noomhorm A. Study on enhanced absorption of phenolic compounds of Lactobacillus-fermented turmeric (Curcuma longa Linn.) beverages in rats.
  • Hur SJ, Lee SY, Kim Y-C, Choi I, Geun-Bae Kim G-B. Effect of fermentation on the antioxidant activity in plant-based foods. Food Chem 2014; 160:346-56.
  • Bresciani L, Favari C, Calani L, Francinelli V, Riva A, Petrangolini G, Allegrini P, Mena P, Del Rio D. The Effect of Formulation of Curcuminoids on Their Metabolism by Human Colonic Microbiota. Molecules 2020; 25(4): 940.
  • Eun C-S, Lim J-S, Lee J, Lee S-P, Yang S-A. The protective effect of fermented Curcuma longa L. on memory dysfunction in oxidative stress-induced C6 gliomal cells, proinflammatory-activated BV2 
  • microglial cells, and scopolamine-induced amnesia model in mice. BMC Complement Altern Med 2017; 17(1):367.
  • Kim Y, You Y, Yoon H-G, Lee Y-H, Kim K, Lee J, Kim MS, Kim J-C, Jun W. Hepatoprotective effects of fermented Curcuma longa L. on carbon tetrachloride-induced oxidative stress in rats. Food Chem 2014; 151:148-53.
  • Yong CC, Yoon Y, Yoo HS, Oh S. Effect of Lactobacillus Fermentation on the Anti-Inflammatory Potential of Turmeric. J Microbiol Biotechnol 2019; 29(10):1561-1569
  • Archana R, Namasivayan A. Antistressor effect of Withania somnifera. J Ethnopharmacol 1999; 64:91-93.
  • Bone K. Clinical Applications of Ayurvedic and Chinese Herbs. Monographs for the Western Herbal Practitioner. Australia: Phytotherapy Press; 1996:137-141.
  • Chihiro Tohda and Eri Joyashiki. Sominone enhances neurite outgrowth and spatial memory mediated by the neurotrophic factor receptor, RET. British Journal of Pharmacology (2009), 157, 1427–1440
  • Dadkar VN, Ranadive NU, Dhar HL. Evaluation of antistress (adaptogen) activity of Withania somnifera (Ashwagandha). Ind J Clin Biochem 1987,2:101-108.
  • Mohammad Hossein Mirjalili, Elisabeth Moyano, Mercedes Bonfill, Rosa M. Cusido and Javier Palazón. Steroidal Lactones from Withania somnifera, an Ancient Plant for Novel Medicine. Molecules 2009, 14, 2373-2393;
  • Narendra Singh, Mohit Bhalla, Prashanti de Jager and Marilena Gilca. An overview on ashwagandha: a rasayana (rejuvenator) of Ayurveda. Afr J Tradit Complement Altern Med. (2011) 8(S):208-213 208
  • Shruti Bhasin, Manali Singh and Dipti Singh. Review on bioactive metabolites of Withania somnifera. (L.) Dunal and its pharmacological significance. Journal of Pharmacognosy and Phytochemistry 2019; 8(3): 3906-3909
  • Singh N, Nath R, Lata A, et al. Withania somnifera (ashwagandha), a rejuvenating herbal drug which enhances survival during stress (an adaptogen). Int J Crude Drug Res 1982; 20:29-35.
  • Tomoharu Kuboyama, Chihiro Tohda, and Katsuko Komatsu. Effects of Ashwagandha (Roots of Withania somnifera) on Neurodegenerative Diseases. Pharm. Bull. 37(6) 892–897 (2014) Vol.37
  • Biswas T, Mathur AK, Mathur A. A literature update elucidating production of Panax ginsenosideswith a special focus on strategies enriching the anti-neoplastic minor ginsenosides in ginseng preparations. Appl Microbiol Biotechnol 2017; 101(10):4009-4032.
  • Chang JD, Mantri N, Sun B, Jiang L, Chen P, Jiang B, Jiang Z, Zhang J, Shen J, Lu H, Liang Z. Effects of elevated CO2 and temperature on Gynostemma pentaphyllum physiology and bioactive compounds. J Plant Physiol 2016; 196-197:41-52.
  • Choi EK, Won YH, Kim SY, Noh SO, Park SH, Jung SJ, Lee CK, Hwang BY, Lee MK, Ha KC, Baek HI, Kim HM, Ko MH, Chae SW. Supplementation with extract of Gynostemma pentaphyllum leaves reduces anxiety in healthy subjects with chronic psychological stress: A randomized, double-blind, placebo-controlled clinical trial. Phytomedicine 2019; 52:198-205.
  • Cui J, Eneroth P, Bruhn JG. Gynostemma pentaphyllum: identification of major sapogenins and differentiation from Panax species. Eur J Pharm Sci 1999; 8(3):187-91.
  • Hussain A, Bose S, Wang JH, Yadav MK, Mahajan GB, Kima H. Fermentation, a feasible strategy for enhancing bioactivity of herbal medicines. Food Res Int 2016; 81:1-16.
  • Huyen VT, Phan DV, Thang P, Hoa NK, Ostenson CG. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients. J Nutr Metab 2013; 2013:765383.
  • Huyen VT, Phan DV, Thang P, Ky PT, Hoa NK, Ostenson CG. Antidiabetic Effects of Add-On Gynostemma pentaphyllum Extract Therapy with Sulfonylureas in Type 2 Diabetic Patients. Evid Based Complement Alternat Med 2012; 2012:452313.
  • Kim EH, Kim W. An Insight into Ginsenoside Metabolite Compound K as a Potential Tool for Skin Disorder. Evid Based Complement Alternat Med 2018; 2018:8075870.
  • Kim JH, Yi YS, Kim MY, Cho JY. Role of ginsenosides, the mainactive components of Panax ginseng, in inflammatory responses and diseases. J Ginseng Res 2017; 41(4):435-443.
  • Li Y, Lin W, Huang J, Xie Y, Ma W. Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan). Chin Med 2016; 11:43.
  • Lokman EF, Gu HF, Wan Mohamud WN, Östenson CG. Evaluation of Antidiabetic Effects of the Traditional Medicinal Plant Gynostemma pentaphyllum and the Possible Mechanisms of Insulin Release. Evid Based Complement Alternat Med 2015; 2015:12057
  • Marín-Aguilar F, Pavillard LE, Giampieri F, Bullón P, Cordero MD. Adenosine Monophosphate (AMP)-Activated Protein Kinase: A New Target for Nutraceutical Compounds. Int J Mol Sci 2017; 18(2).
  • Morgunova GV, Klebanov AA. Age-related AMP-activated protein kinase alterations: From cellular energetics to longevity. Cell Biochem Funct 2019; 37(3):169-176.
  • Nguyen PH, Gauhar R, Hwang SL, Dao TT, Park DC, Kim JE, Song H, Huh TL, Oh WK. New dammarane-type glucosides as potential activators of AMP-activated protein kinase (AMPK) from Gynostemma pentaphyllum. Bioorg Med Chem 2011; 19(21):6254-60.
  • Park SH, Huh TL, Kim SY, Oh MR, Tirupathi Pichiah PB, Chae SW, Cha YS. Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): a randomized, double-blind, placebo-controlled trial. Obesity (Silver Spring) 2014; 22(1):63-71.

See our other products

Disclaimer

Please note that this website is not directed to end consumers as the information may contain statements or product ratings that do not apply to your country. No website on the internet should be considered a substitute for professional medical care. You are solely responsible that the product and ingredients are in compliance with all applicable laws and regulations, and authorities of your country before the finished product is sold. Corporations using this information in relation to their branded products should seek their own legal advice as part of due diligence.

The information is intended for healthcare professionals and agencies and in a non-commercial context only. By continuing, you acknowledge that the information should not be used in communication for targeting consumers.

Users of this material should be aware that the use of this information in a different context or modification such as changes in the wordings or copy any text, omissions or additions, as well as adding pictorials, can have legal consequences. Biocell Medic shall therefore have no liability whatsoever in these circumstances, including any loss or damage resulting from the use of this document or the information contained herein.


The statements refer to the information about our products, ingredients, and formula, and may not be in accordance with Regulation (EC) No. 1924/2006 or other provisions in force in your country. No guarantees are made for the effectiveness of any products mentioned in this website. The products sold on this site have speculative benefits and could have side effects. This is true of any dietary supplement or over the counter product. Because the human body reacts differently to supplements for different people, just as prescription medications could, essentially, we not warrant the accuracy of the information or guarantee the claims, benefits or safety of specific products sold. Content on our website is not intended to be used to diagnose, treat, cure, or prevent any disease or health condition or to substitute advice given by medical practitioners, pharmacists or other licensed health care professionals. You should contact your health care provider immediately if you suspect that you have any medical problem. Always consult your physician before taking Food Supplements, especially if you are taking medication, have an existing medical condition or are due to undergo surgery.  You should not take food supplements as a substitute for a varied balanced diet or a healthy lifestyle. Not suitable for pregnant or lactating women unless directed by a physician.


The producer of a finished product is responsible for compliance with applicable laws and regulations of their country or countries, before the finished product is sold.


International customers agree to be sure of the following and must accept these terms: all rules of Customs and clearance to receive our products are the sole responsibility of the customer. We are not responsible and cannot be held liable for packages which are confiscated by Customs, or misuse of the products. We will not replace any items seized by the customs department of any country. All items shipped to countries are shipped totally at the risk of the customer, and will not necessarily be reimbursed or replaced if the items are lost, stolen, or confiscated. We reserve the right to add insurance to any order being shipped to protect the interests of both, ourselves and the consumer. Thanks for understanding. It is very important to know that these statements have not been evaluated by the Food and Drug Administration.


For extra ensuring, the product is not intended to diagnose, treat, cure, or prevent any disease. The information provided on this site is for informational purposes only and is not intended as a substitute for advice from your physician or other health care professional or any information contained on or in any product label or packaging. You should not use the information on this site for diagnosis or treatment of any health problem or for proscription of any medication or other treatment. You should consult with a healthcare professional before starting any diet, exercise, or supplementation program, before taking any medication, or if you have or suspect you might have a health problem. You should not stop taking any pharmaceutical product without first consulting your prescribing physician.


For extra securing, the information in this website is intended for healthcare professionals and agencies and in a non-commercial context only. By continuing, you acknowledge that the information should never be used in communication for targeting consumers.


The vendors and producers of a finished products, ingredients, and formula, are responsible for compliance with all applicable laws and regulations of their countries before the finished product is sold.